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DARTS
Radiation Therapy followed by Durvalumab (MEDI4736) and Tremelimumab And Surgery versus Radiation Therapy followed by Surgery for Resectable Hepatocellular Carcinoma. A Randomized Window of Opportunity Trial (DARTS) Principal Investigator(s): Dr. Pablo Serrano
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ELISA
Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ Defined by a Molecular Expression Assay Combined with Clinico-Pathological Features Principal Investigator(s): Dr. Eileen Rakovitch, Dr. Tim Whelan
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EMBRACE
A Study of Elranatamab Management with Outpatient and Intermittent Dosing in Relapsed/Refractory Multiple Myeloma Principal Investigator(s): Dr Hira Mian
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PREVENT-iT
Prospective Randomized Evaluation of Emerging Novel Treatments for Infection Prophylaxis in Total Joint Replacement Principal Investigator(s): Dr Thomas Wood
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RAPID2
A Randomized Trial of Five-Fraction Partial Breast Irradiation Principal Investigator(s): Dr. Tim Whelan
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ROSALIE
Radiation Omission in Patients with Clinically Node Negative Breast Cancer Undergoing Lumpectomy and with a PathologIc Complete Response after Neoadjuvant Chemotherapy Principal Investigator(s): Dr. Elena Parvez
Trials Research & Clinical Evidence
Trials Research and Clinical Evidence (TRACE) (home of the Ontario Clinical Oncology Group) is an academic clinical trial unit affiliated with the Faculty of Health Sciences at McMaster University and Hamilton Health Sciences. We work with Investigators to design and conduct high quality clinical trials through collaboration, scientific and methodological rigour and operational excellence. We collaborate across a broad range of clinical areas, bringing specialized strengths in oncology and venous thrombosis.
Come Collaborate With Us
We partner with academic institutions, healthcare organizations, and industry to design and evaluate interventions across diverse clinical settings. Our collaborative approach spans from initial protocol development through study completion and results dissemination.
To explore collaboration opportunities, Please submit the request to tracetrials@mcmaster.ca. Requests must be received at least 8-12 weeks before any funding application deadline.
